Our Vision

Recognized global leader in funding a comprehensive portfolio of research to meaningfully improve memory, cognition, and independence in individuals with Down syndrome.

The mission of the LuMind Research Down Syndrome Foundation is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition, including memory, learning and speech, for individuals with Down Syndrome.

Our Approach  Learn More

How Your Donation Helps

Cognition research offers opportunities for people of all ages with Down syndrome. Your support is essential to finding safe, effective therapies to improve cognition and delay the onset of Alzheimer’s disease within the Ds community. Your gift is crucial to furthering these breakthroughs.

By the Numbers

Down syndrome in our community and the world.

US Statistics


The number persons with Down syndrome in the US

Worldwide Numbers


Estimated number of people with Down syndrome worldwide

Dollars per person


The amount of private research dollars spent in the US in 2015 per diagnosed person with Down syndrome

LuMind RDS News

AC Immune, UCSD, NIH and LuMind RDS Collaborate on 3 Star Trial

The 3 Star Study is investigating whether a vaccine can affect Alzheimer’s disease-related brain changes in people with Ds. The trial is designed for adults with Ds who meet the following criteria: Are 25 to 45 years of Age Do not have any other serious illness Have a caregiver/informant who can answer questions about you …

Read More

LuMind RDS Sponsors T21RS Meeting: A Global Approach to Down Syndrome Research

This year, LuMind RDS is excited to be a Main Sponsor of the 2017 Trisomy 21 Research Society (T21RS) Conference from June 8 through 11 at the Feinberg School of Medicine of Northwestern University in the heart of the city of Chicago. Speakers represent Basic, Translational and Clinical Researchers and Funders from public and private sources. This …

Read More

Dr. Edgin is Racing to Make A Difference in Cognition

When Dr. Edgin started thinking about running, she was motivated by a desire to get stronger and healthier.  She had begun to notice the effects of neglecting exercise while she balanced her family duties with a full schedule as an assistant professor at the University of Arizona and as the Director of Memory Development Disorders Laboratory. However, …

Read More

What people are saying about us.

“I never thought I would be in a position to say, ‘We are going to take therapies forward to directly treat Down syndrome.’ Now I think that is the case. We really are in the early stages of a revolution in understanding the basis for many of the features that occur in Down syndrome.”

Dr. Roger Reeves, Johns Hopkins