Our Vision

Bringing light to the science of cognition research.

The mission of the LuMind Research Down Syndrome Foundation is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition, including memory, learning and speech, for individuals with Down Syndrome.

Our Approach  Learn More

How Your Donation Helps

Cognition research offers opportunities for people of all ages with Down syndrome. Your support is essential to finding safe, effective therapies to improve cognition and delay the onset of Alzheimer’s disease within the Ds community. Your gift is crucial to furthering these breakthroughs.

By the Numbers

Down syndrome in our community and the world.

US Statistics

250,000 - 400,000

The number persons with Down syndrome in the US

Worldwide Numbers


Estimated number of people with Down syndrome worldwide

Dollars per person


The amount of research dollars per diagnosed person with Down syndrome

LuMind RDS News

LuMind RDS Foundation Awards More Than $1.6 Million in New Grants for Cognition Research for Individuals with Down Syndrome

LuMind™ Research Down Syndrome Foundation (LuMind RDS) — formerly the Down Syndrome and Treatment Foundation and Research Down Syndrome — advances Down syndrome (Ds) cognition and Alzheimer’s disease (AD) research with $1,615,000 in funding awards for seven new research grants in 2017. Since 2004, LuMind RDS has raised more than $15 million and funded research …

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Meet our San Francisco Runners

We’re so excited to cheer on our runners participating in the San Francisco Marathon, Half Marathon, and 5k races this weekend! Please join us in supporting Megan Mozart, Leyda Simon, Reyna and Eduwin Rodriguez as they take on a hilly 26.2 miles Sunday morning. Megan began running with LuMind RDS Runners four years ago after …

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What people are saying about us.

“I never thought I would be in a position to say, ‘We are going to take therapies forward to directly treat Down syndrome.’ Now I think that is the case. We really are in the early stages of a revolution in understanding the basis for many of the features that occur in Down syndrome.”

Dr. Roger Reeves, Johns Hopkins