Promising Alzheimer’s drugs are
ready for late-stage clinical trials

Virtually all adults with Ds develop the neuropathology (amyloid beta plaques and tau tangles) consistent with Alzheimer’s by their 40s. At age 40, 10% already have Alzheimer’s dementia. Without necessary resources, Pharma will not be able to measure how well any therapies work for people with Down syndrome and will delay the initiation of late stage clinical trials in Down syndrome with their promising Alzheimer’s therapies.

LuMind RDS has funded a grant to support the planning effort required to establish a Down Syndrome Clinical Trial Consortium, focused initially on advancing Alzheimer’s therapies for individuals with Down syndrome.

Your Donation Helps

Down syndrome research offers opportunities for people of all ages with Down syndrome. Your support is essential to finding safe, effective drugs and interventions to improve health and independence. Your gift is crucial to furthering these breakthroughs.

We’ve designed a clear path to therapies

Based on recent scientific findings, our CEO, board and world renowned scientific advisors have established four priorities for funding research. We’re focused on exciting research targeting the root cause with the objective of improving health and independence for our loved ones throughout their lifetimes. Our four priorities are: preventing Alzheimer’s onset, improving cognition, developing gene therapies, and advancing understanding.

LuMind RDS News

Increased Commitment to Down Syndrome Research Included in 2018 Omnibus Spending Bill

New trans-NIH Down Syndrome Initiative aims for scientific discoveries to improve the health and neurodevelopment of individuals with Down syndrome LuMind™ Research Down Syndrome Foundation (LuMind RDS) joins other Down syndrome organizations in applauding Congress on including a major milestone for Down syndrome research as part of the final Fiscal Year 2018 Omnibus Appropriations legislation, …

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Welcome to the Team, Margie Doyle.

I am thrilled to join the LuMind RDS staff. As Director of Development and Research Sponsorship, I will lead the expansion of LuMind RDS’ special events and corporate sponsorship initiatives. I believe growing support for Down syndrome research is the key to improved health and independence for all individuals with Down syndrome. Like many of …

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What people are saying about us.

“I never thought I would be in a position to say, ‘We are going to take therapies forward to directly treat Down syndrome.’ Now I think that is the case. We really are in the early stages of a revolution in understanding the basis for many of the features that occur in Down syndrome.”

Dr. Roger Reeves, Johns Hopkins