Our Vision

Recognized global leader in funding a comprehensive portfolio of research to meaningfully improve memory, cognition, and independence in individuals with Down syndrome.

The mission of the LuMind Research Down Syndrome Foundation is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition, including memory, learning and speech, for individuals with Down Syndrome.

Our Approach  Learn More

How Your Donation Helps

Cognition research offers opportunities for people of all ages with Down syndrome. Your support is essential to finding safe, effective therapies to improve cognition and delay the onset of Alzheimer’s disease within the Ds community. Your gift is crucial to furthering these breakthroughs.

By the Numbers

Down syndrome in our community and the world.

US Statistics


The number persons with Down syndrome in the US

Worldwide Numbers


Estimated number of people with Down syndrome worldwide

Dollars per person


The amount of private research dollars spent in 2015 per diagnosed person with Down syndrome

LuMind RDS News

A Tribute to Dr. Michael Harpold

Scientist, Advocate and Friend   Dr. Michael Harpold was Chief Scientific Officer of the LuMind Research Down Syndrome Foundation, and served as Chair of the Foundation’s Scientific Advisory Board since its inauguration in 2006. He was involved with LuMind since 2005, and served as member of the Board of Directors (2006-2010), Chief Executive Officer (2007-2010), and Chief …

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For their son and the thrill of the Race!!

Meet Matt and Angela, who coincidentally celebrated 2017 World Down Syndrome Day http://events.LuMindRDS.org/2017WorldDownSyndromeDay by running the NYC 1/2 Marathon.  After all the hard work of training and fundraising is done, all that is left is the Thrill of crossing the finish line. Thank you for sharing your great experience with us!                    #lumindrdsCARES  #Race4eXtraordinary Where do I even …

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Meet Kaylee, the runner with Down Syndrome that never quits!

Everyone worries that they won’t finish their race in time but that didn’t stop a young lady from Texas with Down Syndrome.  Well meet Kaylee, her story will inspire even the biggest running critic to lace us their shoes and get outside.  Kaylee and her mom started running to get healthy like most of us, …

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What people are saying about us.

“I never thought I would be in a position to say, ‘We are going to take therapies forward to directly treat Down syndrome.’ Now I think that is the case. We really are in the early stages of a revolution in understanding the basis for many of the features that occur in Down syndrome.”

Dr. Roger Reeves, Johns Hopkins