Kennedy Krieger awarded $8.5 million to study aging and dementia in adults with Down syndrome

Categories: News

The NIH recently announced it has awarded the Kennedy Krieger Institute an $8.5 million grant to address crucial gaps in knowledge about Alzheimer’s disease in adults with Down syndrome. This will allow the Baltimore based institute to undertake a variety of projects to extend the understanding of the onset and progression of Alzheimer’s disease within …

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University of Arizona news item summarizes Down syndrome cognitive test battery

Categories: News

Our news section included a story August 18th about the development of a battery of tests that is an important advance as Down syndrome cognitive research approaches clinical trials in humans. Here is an article in the University of Arizona news that provides a very readable account of this advance. The article notes that the …

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A collaborative approach to Alzheimer

Categories: News

Alzheimer’s disease(AD) is far more common in persons with Down syndrome than the general population. Most, if not all, persons with Down syndrome begin to exhibit the brain pathology associated with AD by the age of forty. The onset of AD occurs earlier in persons with Down syndrome, and its prevalence reaches up to 75% …

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Scientists identify additional cancer blocking genes on chromosome 21

Categories: News

“It’s incredibly inspiring to know that by studying the genetic make-up of people with Down’s Syndrome we have been able to make important discoveries that help us understand far more about the intricate processes involved in cancer tumour growth.” So states Professor Kairbaan Hodivala-Dilke, from Queen Mary, University of London, commenting on her recently published …

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Reducing Alzheimer

Categories: News

Here is a summary of a study from the UT Southwestern Medical Center that describes the effective use of a drug targeted to improve learning in a mouse model. In this study, a drug which reduces beta-amyloid protein by 40 percent allowed mice to learn a standard water maze as quickly as control mice.