AC Immune, UCSD, NIH and LuMind RDS Collaborate on 3 Star Trial

Categories: Clinical Trials, Ds Research, News, Other

The 3 Star Study is investigating whether a vaccine can affect Alzheimer’s disease-related brain changes in people with Ds. The trial is designed for adults with Ds who meet the following criteria:

  • Are 25 to 45 years of Age
  • Do not have any other serious illness
  • Have a caregiver/informant who can answer questions about you

The study is a randomized, placebo-controlled, double-blinded study. This means that study participants will be randomly given either the active investigational vaccine or a non-active placebo that looks like the active drug; neither the participant nor the study personnel at the clinic will know who is receiving which one.

The study will last 24 months, during which study participants will visit the study clinic 21 times. At each visit, participants will be asked how they are feeling, and at some of the visits they will undergo medical exams, memory tests, blood tests, lumbar punctures (optional), ECG and brain imaging scans. The investigational vaccine and research visit procedures are free of charge. Travel costs will be paid.

Interested in learning more about the 3 Star Trial?

Here are three academic medical centers and specialty clinics participating in the 3 Star Study.

Barrow Neurological Institute Phoenix, AZ Sandy Quintanilla
Study Coordinator
Barrow Neurological Institute
(602)406-7054
Sandy.Quintanilla@DignityHealth.org
 
Massachusetts General Hospital Boston, MA AmyTorres

Study Coordinator   

(617)726-7927

aetorres@partners.org

 

 
University of California, San Diego San Diego, CA Holly Hainley, NP
UCSD DS Center for Research & Treatment
(858) 249-2527
hbhainley@ucsd.edu